This chapter first reviews essential features of A Framework for K–12 Science Education which provides a foundation for the Next Generation Science Standards (NGSS). Second, the chapter describes the important features of NGSS and introduces the NGSS using the life sciences as the context for deeper discussions of important content, some challenges, and several opportunities faced by K–12 teachers of science. Teacher background information, standards, assessments, and references are provided. This book selection also includes the Table of Contents, Foreword, Preface, About the Author, Introduction, Appendix D, and Index.