This lesson helps students: develop and use a model to explain the inheritance of traits; predict the frequency of genotypes and phenotypes in a cross; recognize that each parent contributes equally to the genotype even when the recessive trait is not reflected in the phenotype; represent the inheritance of a trait in a pedigree diagram; explain how a single Mendelian trait is inherited; explain that mutations cause changes in proteins that may be beneficial, harmful, or have no effect on an individual; use research skills to learn about heritable disease; an identify the central ideas of a text. The investigations support the Next Generation Science Standards and the Common Core State Standards. This book selection includes the Table of Contents, About the Authors, Introduction, and Index.