Unless a middle school facility was built fewer than 20 years ago, chances are it was originally designed and built for another purpose—a solution to an enrollment or facility problem—not an educational concept. But for inquiry-based middle school science, the configuration and condition of science facilities are critical components of a safe and successful program, as well as limiting the number of students in the class. This chapter offers the recommended facilities standards for middle school science. If the ideal conditions cannot be achieved right away, it’s essential to set goals and modify programs working toward the recommended standards.