Carefully selected trade books can introduce science concepts, develop background knowledge, reinforce hands-on lessons, support science-process skills, and at the same time enhance related literacy-process skills. They can also provide inspiration and structure for integrated science and literacy lessons. Based on these ideas, the authors developed the Science and Literacy Framework, which enables teachers to plan integrated lessons that capitalize on the similarities between science processes and literacy processes. This article describe three experiences from several hundred teachers who used the framework to build successful integrated lessons in their K—6 classrooms.