This case study introduces undergraduate students to Wolff-Parkinson-White (WPW) syndrome, a rare but clinically significant congenital cardiac condition characterized by abnormal electrical conduction in the heart. The case centers on a 29-year-old female patient whose symptoms develop progressively, allowing students to apply concepts in real time as the scenario unfolds. Designed for students in human anatomy, physiology, and pre-health science programs, the case promotes active learning through an interrupted case method, where information is revealed in stages to encourage ongoing analysis, discussion, and critical thinking. Students interpret realistic clinical data, including vital signs and electrocardiograms (ECGs), to distinguish between normal and WPW presentations. They also examine the heart’s electrical conduction system, investigate the ionic mechanisms underlying cardiac muscle contraction, and assess treatment options such as procainamide therapy and catheter ablation. By working through this case, students will deepen their understanding of cardiovascular physiology, enhance their ECG interpretation skills, and develop clinical reasoning abilities applicable to patient care settings.