In this case, students are shown the relevance of chemistry in daily decision-making by taking a look at the popular dietary supplement, s-adenosylmethionine (SAMe), widely used in Europe for depression, arthritis, and liver disease and now available in the United States.  The case was developed for use in the first semester of a general biology course taken primarily by non-science majors. Designed to introduce these students to chemistry, it is also good for developing critical thinking skills with regard to the use of dietary supplements, which tend to be popular with many students.