Alvin’s parents are worried about him. He has had a cough for almost a week, and he’s wheezing a lot more than they think is normal for a child with a cold, which is what their family pediatrician says he has. When they take him to the ER, however, the pediatric pulmonologist on duty tells them their son is suffering from something much more serious than a cold. This case study was developed for second-year pharmacy students to help them tie together elements of cell physiology, osmosis and tonicity, and membrane transport processes. The questions, which focus on disease mechanisms, symptoms, and treatment options, could be modified for non-pharmacy students.