Students assume the roles of CDC researchers who must determine how to most effectively stop an impending Zombie apocalypse. The story line leads students through the process of developing a mathematical model of a Zombie outbreak, which they then use to evaluate different "management" strategies to ensure human survival. Students are introduced to a flow diagram, learn how to derive equations from a flow diagram, and evaluate predictions of the model. Comparisons to the spread of invasive species, infectious disease outbreaks, and predator-prey relationships help the students to see how important biological processes can be modeled quantitatively. Since the focal species (zombies) is fictitious, this case is an ideal way to introduce students to the process of mathematical modeling without worrying about the system-specific details of any particular organism. Originally designed for a second year introductory ecology course, this case is also appropriate for an epidemiology course, advanced population ecology courses, applied ecology courses, and quantitative biology/mathematical biology courses.