Nancy has been looking forward to her retirement and a chance to entertain and travel with her husband Jim. But she hasn’t been feeling well. She’s often tired, and recently she’s been experiencing a burning sensation in her lower chest as well as nausea and difficulty breathing. This case was designed for an introductory human biology, anatomy and physiology, or health and wellness course. Its overall purpose is to identify some healthy and not-so-healthy lifestyle choices and the consequences of those choices. It also serves to demonstrate that men and women suffering from the same disease often experience different symptoms.