Hemophilia

By Yelena Aronova-Tiuntseva, Clyde Freeman Herreid

Abstract

This case deals with the genetics of the hemophilic condition that afflicted the royal families of Europe. Students trace the pedigrees of the descendants of Queen Victoria and the passage of the recessive X-linked trait from ancestor to ancestor. The case is suitable for courses in general biology at either the high school or college level.

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Date Posted

05/01/1999

Overview

Objectives

Provide a real example of pedigree analysis of a sex-linked trait.
Provide students an opportunity to calculate probabilities of the transmission of a genetic trait.

Keywords

Hemophilia; haemophilia; hemophiliac; recessive disorder; genetic disease; sex-linked trait; blood; hemoglobin; Queen Victoria; Tsarevich Alexei Nikolaevich; Romanovs

Subject Headings

Biology (General)

Genetics / Heredity

Medicine (General)

EDUCATIONAL LEVEL

High school, Undergraduate lower division

FORMAT

PDF

TOPICAL AREAS

N/A

LANGUAGE

English

TYPE/METHODS

Directed, Discussion, Interrupted

Teaching Notes & Answer Key

Teaching Notes

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Answer Key

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