This case study is designed to help students better understand chemical bonds by introducing them to perfluoroalkyl and polyfluoroalkyl substances (PFAS), often referred to as “forever chemicals.” The unique structure of these substances renders them practically non-biodegradable due to the presence of the carbon-fluorine (C-F) bond, the strongest bond in organic chemistry. The case tells the story of “Kayla Bond,” a biochemistry major, who learns of her mother’s diagnosis of type 2 diabetes and wonders whether it could be a consequence of PFAS contamination in their hometown water supply. To find out whether there is a connection, Kayla investigates what makes the C-F bond so strong, and in the process deepens her understanding of concepts such as electronegativity, atomic radius, bond length, dipole moment, and bond enthalpy. Originally developed for biology, biochemistry, and health science majors in an introductory chemistry course, the case could also be adapted for general chemistry or environmental science courses.