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Types of cases are defined as follows: Analysis/Issues, Clicker, Debate, Intimate Debate, Demonstration, Dilemma/Decision, Directed, Discussion, Interrupted, Jig-saw, Journal Article, Laboratory, Student Presentations, Mini-case, Problem-Based Learning, Public Hearing, Role-Play, Trial, Flipped, Game

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Is It a Meteorite?

By Maryuri Roca

In this interrupted case study, two friends find unanalyzed mass spectra of a green rock suspected to be a meteorite. Students are tasked with identifying the elements present in the meteorite by analyzing the mass spectra. The purpose of this case i...

Penicillin

By Elizabeth C. Leininger

This case study uses the discovery and molecular structure of penicillin to teach basic chemistry concepts as they apply to biological and biologically-active molecules. Topics covered include the elements found in living things, electronegativity an...

Why Homeostasis Is Important to Everyday Activities

By Brian J. Dingmann

In this case study, a college student named "Blake" winds up in the emergency room after he experiences a panic attack brought on by drinking a mixture of beverages containing caffeine and alcohol. His panic attack results in a severe episode of hype...

Organic Food

By Suzanne R. Carpenter, Richard H. Wallace

Currently there is considerable confusion surrounding the use of the term "organic" as applied to food and other consumer products, but within the agriculture industry the term has a well-defined meaning related to the practices that are allowed in t...

The Flint Water Crisis

By Tracy J. Terry

The water crisis in Flint, Michigan, provides a compelling context for understanding the importance of each of the major classes of chemical reactions: precipitation reactions, acid-base reactions, and oxidation-reduction reactions. Each of these rea...

Bioluminescence and 16th-century Caravaggism

By Yunqiu (Daniel) Wang

This case study looks at the probable connection between bioluminescence and Caravaggio's painting style in the 16th century in order to explore the mechanism of bioluminescence and its role in animal evolution and modern medicine. Recent studies hav...

Let's Get This Course Started

By Karen K. Bernd, Cindy D. Hauser, Kristie L. Foley

The first day of class is often a reading of the syllabus, even when active learning approaches are used throughout the rest of the term. This interrupted case uses the first day to model the expectations of a course that uses case method approaches....

Developing a Holistic Understanding of Hybridization and Resonance

By Manisha Nigam

This case study is the result of the author's efforts to help students master the complex concept of resonance by unifying multiple concepts across general chemistry and organic chemistry courses. Resonance is a key building block for students' under...

The Never-Ending Contamination

By Lior M. Burko

This case study discusses a possible national security crisis of a terrorist group stealing radioactive materials in an attempt to build and detonate a dirty bomb over a densely populated metropolitan area. Specifically, this case discusses radioacti...

BSL-4: Authorized Personnel Only

By Nicole M. Anthony

This case study is based on the 2014 Ebola epidemic that spread to multiple highly populated countries in West Africa, making it the largest and most devastating outbreak in the history of the virus. The storyline, inspired by a compilation of factua...

The Spark of Life

By Annie Prud’homme-Genereux, Nicole F. Magill, Tatiana N. Bliss

In biology classes, students are typically taught that spontaneous generation does not take place. And yet, at the origin of life, life had to arise without parents from abiotic processes. What were those processes that gave rise to the first life?&n...

Deflategate

By Daniel R. Albert

This case study involves analysis of data collected as part of the National Football League's investigation into the New England Patriots allegedly deflating footballs to gain a competitive advantage in a 2015 playoff game. The scandal and subsequent...

Fuel from Water and the Sun

By Joshua D. Hartman, Jack F. Eichler

This problem-based case study presents recent advancements in the development and application of technologies geared towards harnessing sunlight for the production of hydrogen from water. A PowerPoint presentation introduces the topic with a New York...

Bonding with the Tutor

By William Yee, Kevin M. Bonney

This case study presents the story of "Nick," a student who has been assigned the task of writing a research paper describing the fundamentals of chemical bonds and how they relate to human life. When Nick experiences difficulty remembering informati...

Properties of Gases

By Eric J. Herrera

In 2012, Mike Prickett, a world-renowned underwater cinematographer, was working on a commercial photo shoot in Tahiti when he witnessed a fellow diver sinking and drowning. While saving the drowning victim, Mike fell victim to decompression sickness...

A Case of Medication Error

By Brahmadeo Dewprashad

This case study begins with a real news article about a six-month-old baby who died from an overdose of medication administered by hospital staff. The infant was diagnosed with pneumonia and given an intravenous dose of the antibiotic azithromycin, t...

Setting Water on Fire

By Margaret M. Larrousse

This case study is used to teach undergraduate students about hydraulic fracturing (hydrofracking), a controversial method for extracting methane from shale. The controversy arises from claims that chemicals used in the fracking process and the metha...

Hydrogen Powered Cars

By Joshua D. Hartman, Jack F. Eichler

This problem-based case study guides students through a systematic exploration of the scientific issues surrounding the application and development of hydrogen fuel technology. A PowerPoint presentation introduces a New York Times article about the i...

Corn Ethanol

By Joshua D. Hartman, Jack F. Eichler

This problem-based case study guides students through a systematic exploration of the scientific issues surrounding the production and development of bio-fuels. A PowerPoint presentation introduces a New York Times article outlining the impact curren...

Using Oceans to Fight Global Warming?

By Joshua D. Hartman, Jack F. Eichler

This problem-based case study explores the scientific issues surrounding the use of large scale iron fertilization as a means of decreasing atmospheric levels of carbon dioxide.  A PowerPoint presentation introduces a New York Times article abou...

Cow of the Future

By Richard C. Stewart, Daniel C. Stein, Kevin S. McIver, John Buchner, Ann C. Smith

In this case developed for an introductory general microbiology course, students consider concepts of bacterial genetics as they act as consultants to a foundation interested in funding innovative products. Students take the role of advising "the bar...

Breeding Belyaev's Pets

By J. Phil Gibson

This clicker case addresses several important concepts related to evolution. First, it explores artificial selection and selective breeding. Charles Darwin used artificial selection as an example to support his Theory of Evolution by Natural Selectio...

A Curious Mission

By Carly N. Jordan, Elizabeth A. Flaherty, Jonathan F. Prather

In this case study, students play the role of a NASA scientist tasked with analyzing samples of atmosphere and soil collected on Mars as part of the Mars Curiosity Mission. The case study takes place in the future when samples of the Martian atmosphe...

A Struggle for Power in China

By Dan Hua, Brian R. Murphy, Michelle D. Klopfer

The Three Gorges Dam in China is one of the world's largest hydroelectric dams, providing energy for millions of people. However, the dam's construction forever altered the Yangtze River ecosystem and the lives of local residents. In this case study,...

Just a Spider Bite?

By Wayne O. Hatch

This case relates the story of two fictional college students, Kristen and Brent, who discover that they are infected with Staphylococcus aureus. Brent recovers after using an antibiotic, but Kristen does not. It is later confirmed through testing th...

Aliens on Earth?

By Annie Prud’homme-Genereux

The discovery of a bacterium capable of substituting arsenic for phosphorus in its DNA was announced with much fanfare in 2010. It was immediately and very publicly critiqued by researchers posting their analyses of the paper on their blogs. The auth...

Liquid Coal

By Joshua D. Hartman, Kelly Theel, Jack F. Eichler

In this problem-based case study, students systematically explore the scientific issues surrounding the application and development of coal-to-liquid fuel technology. An introductory reading from the New York Times highlights the significant impact t...

Pharmacogenetics: How Genetic Information Is Used to Treat Disease

By Maureen Knabb

In this clicker case, two teenagers are diagnosed with Acute Lymphoblastic Leukemia (ALL), a cancer of the bone marrow where there is an abnormal overproduction of lymphocyte precursors. The girls' reactions to treatment are very different, however, ...

Murder by HIV? Grades 5-8 Edition

By Michèle I. Shuster, Naowarat (Ann) Cheeptham, Laura B. Regassa

This case study gives students an opportunity to draw a conclusion about an actual crime that was prosecuted in Louisiana. A physician was accused of intentionally infecting his ex-girlfriend with HIV-tainted blood drawn from a patient in his practic...

Murder by HIV? Grades 9-12 Edition

By Laura B. Regassa, Naowarat (Ann) Cheeptham, Michèle I. Shuster

This case study gives students an opportunity to draw a conclusion about an actual crime that was prosecuted in Louisiana. A physician was accused of intentionally infecting his ex-girlfriend with HIV-tainted blood drawn from a patient in his practic...

Murder by HIV? Undergraduate Edition

By Naowarat (Ann) Cheeptham, Laura B. Regassa, Michèle I. Shuster

This case study gives students an opportunity to draw a conclusion about an actual crime that was prosecuted in Louisiana. A physician was accused of intentionally infecting his ex-girlfriend with HIV-tainted blood drawn from a patient in his practic...

History of the Atom

By Jack F. Eichler

In this clicker case, students are guided through the history of atomic structure, and in the spirit of discovery learning, use data from historical experiments to discern the different models of the atom. In particular, students move from the time o...

The Molecular Origin of Life: Replication or Metabolism-First? Advanced Version

By Annie Prud’homme-Genereux, Rosalind H. Groenewoud

This case explores both the evidence and inconsistencies in the two major hypotheses for the origins of life on Earth: Replication-First or Metabolism-First. The case has two versions published on this website; one is written at the introductory leve...

Is High Fructose Corn Syrup Bad for the Apple Industry?

By Jeffri C. Bohlscheid

In this interrupted case, students analyze a peer-reviewed article and apply the scientific method to solve an agricultural mystery. A fictional apple farmer and his son are trying to determine if high fructose corn syrup has led to the loss of the b...

The Chemistry of Cocaine

By Brahmadeo Dewprashad

This case study on the chemistry of cocaine is in the form of a classroom discussion between a professor and her students about cocaine, its addictive properties, a search for an addiction treatment, and the chemistry involved in the synthesis of coc...

Fat Facts

By Ling Chen, Lalitha S. Jayant

It's Mother's Day and Dolly, a high school senior, is making a Mediterranean salad for her mom, who is a college chemistry major and who likes to take every opportunity to teach Dolly what she has learned in school. Today is no exception, as she guid...

Sweet Truth

By Ling Chen, Diane R. Wang, Jennifer Y. Anderson

This case reviews concepts of monosaccharide, disaccharide, and polysaccharide and contrasts the structures of different pairs of carbohydrates as well as the structure of sorbitol, a sugar substitute. It also depicts stereo chemistry concepts such a...

The Secret of Popcorn Popping

By Ling Chen, Richard Hendrix

Focusing on the important role of water in living cellular chemistry, this case emphasizes the general solubility rule, "like dissolves like," which explains how water can serve as a medium for transporting the cell's soluble nutrients and wastes. Th...

The Case of the Missing Bees

By Jeffri C. Bohlscheid, Frank J. Dinan

Colony Collapse Disorder (CCD) has claimed approximately one-third of the commercial honeybee population in recent years. A number of causes have been suggested for this phenomenon, including the consumption of high fructose corn syrup (HFCS) by the ...

A Case of Respiratory Distress

By Brahmadeo Dewprashad, Geraldine S. Vaz, Sharon A. Vaz (rr)

This clinical case study was developed to engage students by making connections between core concepts in chemistry and physiological processes in the body. The case pertains to medication-induced methemoglobinemia, its etiology, diagnosis, and treatm...

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