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All Case Studies

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In keyword search, list the criteria you would like to find cases. Multiple criteria can be listed separated by commas (i.e. directed, high school)

Educational levels are defined as follows: Elementary, Middle, High School, College

Types of cases are defined as follows: Analysis/Issues, Clicker, Debate, Intimate Debate, Demonstration, Dilemma/Decision, Directed, Discussion, Interrupted, Jig-saw, Journal Article, Laboratory, Student Presentations, Mini-case, Problem-Based Learning, Public Hearing, Role-Play, Trial, Flipped, Game

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Too Hot to Trot?

By Ashley E. Rhodes, Timothy G. Rozell

This interrupted case study looks at heat stress through the eyes of “Nelly,” a chatty, country Holstein. Although focusing on dairy cattle, the case can be used to teach the physiology of body temperature regulation in any number of homeothermic...

Just Lose It!

By Jody L. Vogelzang, Elizabeth L. MacQuillan, Janna E. Pacey, Geraldine J. Terry, Jeffery A. Trytko, Marie E. VanderKooi

This case study introduces “Rose” and “Michael,” a couple with infertility issues that may be related to Rose’s weight. The story details a visit to a pre-conception clinic and the struggle that Rose and Michael face in addressing underlyin...

An Elderly Anomaly

By M. May Zhang, Maria E. Latta

This case study follows the process of diagnosing a patient, 67-year-old “Chester Fitzgerald,” who has suffered an ischemic stroke. An ECG is performed, but is not conclusive. During a physical exam, his doctor discovers a splenomegaly and orders...

Lacy’s Dry Run

By Ann L. Parkinson, Nicole B. Reinke

This interrupted case study in renal physiology and water balance follows the story of "Lacy," a star athlete, who makes poor fluid intake choices for the duration of a track and field day. Lacy notices changes in the volume and appearance of her uri...

Rhabdomyolysis

By Arne K. Christensen, Joan-Beth Gow

This directed case study focuses on exercise-induced rhabdomyolysis (exRML).  Students are guided though skeletal muscle cell membrane transport and calcium homeostasis.  They are then asked to predict how depletion of ATP at the skeletal m...

A Grumpy Old Man

By Sheri L. Boyce

This directed case study tells the story of an 84-year-old man who has been brought to the ER for treatment of a badly broken wrist. Routine bloodwork reveals his calcium levels are abnormal, which prompts more tests. The results, together with his b...

Why Is My Vision Blurry?

By Julia M. Dais

This interrupted case study is based on the true experiences of the author's mother, who is referred to in the story as "Mrs. Horton" for reasons of privacy. Mrs. Horton, like many seniors, had her life altered due to age-related vision changes. As s...

An Acrid Situation

By Hollie L. Leavitt

This directed case study tells the story of a geriatric patient who has recently been diagnosed with idiopathic pulmonary fibrosis. It begins with him informing his granddaughter, “Jillian,” of the diagnosis. Jillian is a nursing student who is a...

A “Deafinite” Cause for Alarm

By Rebecca T. Garlinger, Patrick K. Mitrano-Towers, Kevin S. Innella, Philip J. Stephens

“Henry” is not the best of patients. He has been admitted into the hospital with bacterial pneumonia, but he soon becomes bored and frustrated by his rate of progress; are the prescribed intravenous antibiotics really doing anything? His solution...

Monkey Brains

By Susan A. Weiner

This case study in comparative physiology explores the connections between physiology, evolution and behavior. Students assume the role of researchers who have discovered the body of a rare and poorly studied (fictional) monkey, Callicebus imagini. S...

A Tradesman’s Journey Back from a Cerebral Incident

By Diana Colgan, Wajid Mirza, Laura Y. Lorentzen, Kristie Reilly

This directed case study tells the story of a middle-aged man with hypertension and hyperlipidemia who experiences an ischemic cerebrovascular accident. The case provides an opportunity for students to integrate the brain's functional anatomy related...

Diabetes and Acid/Base Chemistry

By Eric J. Herrera, Linda M. Roberts

This case study focuses on a teenage patient with type 1 diabetes mellitus (T1DM) who presents with severe acidosis, becomes combative and loses consciousness, and is subsequently treated and released. The scenario is used to teach the topics of meta...

A Tragic Finding

By Anneke M. Metz

This interrupted case study utilizes real patient data and provides students an opportunity to apply knowledge of human metabolism and hormonal control to a complex real-world scenario. The story begins with the discovery of an unconscious patient wh...

Stuck on Repeat

By Carolyn L. Danna

This interrupted case study is based on the real symptoms and laboratory results of a 65-year-old female stroke victim who is obese and on medication for hypertension but has no other significant health issues. The case begins with a description of t...

A Rough Semester

By Thomas E. Hynd, Elizabeth V. Berkeley, Janet C. Daniel, Justin W. Brown, Bisi T. Velayudhan

This interrupted case study tells the story of Katie, an active college sophomore who experiences flu-like symptoms.  She initially thinks that her illness is a result of the stress associated with the rigors of college; however, after visiting ...

Analyzing Clinical Literature

By Rachel A. Jackson, Kimberly S.C. Vogt

Reading and understanding scientific literature can be a daunting task for students in introductory science courses. This decision/dilemma case study helps ease them into the process by using a short scientific article with a simple experimental desi...

A Rainbow of Sepia

By Annie Prud’homme-Genereux

This flipped case study examines the selective pressures that have affected the evolution of diverse human skin pigmentations. To prepare for the case, students begin by watching videos and doing research on their own. In class, students use the info...

Coping with Infection

By Laura A. Schoenle, Cynthia J. Downs

This interrupted case study introduces two distinct, but not mutually exclusive, strategies for defending against parasites: resistance and tolerance. Students analyze and interpret research conducted on resistance and tolerance to gastrointestinal p...

Honeymoon Havoc

By Kaitlin A. Pate, Paul M. Acosta, Melinda A. Payne, Breanna N. Harris

In this interrupted case study, students meet a pair of fictional newlyweds on their way to Australia for their honeymoon. Initially eager to enjoy the sun, sand, and sights, Tanya and Julien Brahim end up more intimately acquainted with the local wi...

I Hate Running!

By Ashley E. Rhodes, Timothy G. Rozell, Abigail R. Wilson

This interrupted worksheet case study, developed for introductory or intermediate undergraduate physiology courses, aims to eliminate misconceptions that many students have about lactate, lactic acid, and changes in the body during exercise. The case...

Barbara’s Thyroid

By Matthew J. Van Sant

This directed case study on thyroid dysfunction was written to help students understand how negative feedback pathways work. The title character suffers from hypothyroidism, and although a specific cause cannot be determined from the information prov...

Know Your Enemy, Know Yourself

By Kelsie M. Bernot, Telah A. Wingate, Kiara D. Whitaker

This case study relates the actual experiences of a woman with breast cancer as she shares her experiences through a series of blog posts at various stages of treatment (diagnosis, mastectomy, chemotherapy, targeted therapy, and maintenance)....

The Mermaid and the Globins

By Nathaniel R. Beres

The function and regulation of hemoglobin is often difficult for students to understand. This directed case study is an attempt to make the topic more approachable by relating the story of “Joanna” and “Alex,” two students who visit their loc...

No Longer Living the Sweet Life

By Noura Farih, Lauren T. Lund, Sara E. Morgan, Johnny M. Turner, Breanna N. Harris

In this interrupted case study, students will help “Dr. Gupta” investigate and assess complications arising in one of her long-term patients, “Jorge Alvarez.” Jorge was diagnosed with Type II diabetes mellitus ten years ago as documented in �...

Scorpion vs. Mouse

By Justin F. Shaffer

This flipped clicker case study explores the fascinating relationship between the Arizona Bark Scorpion (the most venomous scorpion in North America) and the Southern Grasshopper Mouse. Initially it would seem that the grasshopper mouse is no match f...

Going for Gold

By Breanna N. Harris, Wendy Saltzman

This case study introduces students to the true story of Caster Semenya, an outstanding female mid-distance runner from South Africa.  Caster won the 800 m race at the 2009 Track and Field World Championships when she was just 18. Since then, sh...

A Trip to the Eye Doctor

By Hollie L. Leavitt

This directed case study follows a young woman, Samantha, on a routine visit to her eye doctor.  While at her appointment, Samantha receives preventative care and a visual acuity exam while learning more about the anatomy and physiology of her e...

Take a Deep Breath

By Brianna S. Nelson, Kelsey N. Aguirre, Alee L. Adams, Emily E. Brodbeck, Breanna N. Harris

This interrupted case study tells the story of “Callie,” a 26-year-old baker from San Francisco who runs a successful new cupcake business with her fiancé, Jeremey. For some time Callie has not felt well, experiencing fatigue, difficulty breathi...

Do Grasshoppers Sweat?

By John G. Cogan, Emily Hill

There are many adaptive and evolutionary behaviors displayed in an organism's use of water. Although students generally have a superficial understanding of the importance of water to life (i.e., without water life cannot persist), this directed case ...

Fluid in the Ear

By Jason W. Ho, Scott M. Leighow, Sylvie Lee, Philip J. Stephens

This interrupted case study follows the progress of Julius, a singer in a rock band who suffers from severe headaches and pressure in his ears. While visiting his doctor he loses his balance and hits his head as he collapses to the floor. Julius reco...

Caught Red-Handed

By Mackenzie A. Hahn, Hannah C. Schake, Ryan T. Schalles, Sarah R. Shioji, Breanna N. Harris

Was the "Brooklyn Butcher" of 1926 a cold-blooded killer or was something less sinister at play? This interrupted case study introduces students to hemoglobin binding and carbon monoxide poisoning by working through the details of a fictionalized acc...

How to Make ATP

By Monica L. Tischler

This case study for the flipped classroom introduces the discovery process used to elucidate how cells make ATP. Data from three seminal primary literature papers and novel (for their time) methods are used to illustrate how scientists determined the...

Asthma Attack!

By Hollie L. Leavitt

This interrupted case study follows the progress of a pediatric patient who experiences an acute asthma exacerbation brought on by an environmental trigger.  Students completing the case will synthesize their understanding of respiratory system ...

Why Homeostasis Is Important to Everyday Activities

By Brian J. Dingmann

In this case study, a college student named "Blake" winds up in the emergency room after he experiences a panic attack brought on by drinking a mixture of beverages containing caffeine and alcohol. His panic attack results in a severe episode of hype...

Protein Targeting Gone Awry

By Michèle I. Shuster

This case study synthesizes students' knowledge of the central dogma and cell structure by examining a rare health disorder in order to understand protein targeting and its medical consequences. Students first identify the molecular alteration in aff...

The Power of Communication

By Jane P. Sheldon, Diane R. Graves

This directed case study begins with an intentionally ambiguous story: Q suddenly realizes that it is time to relay a message to Z (another inhabitant of their home) to let Z know that it's time to produce some items and send them on to accomplices i...

The Case of the Malfunctioning Neuron

By Kirsten L. Hokeness

This flipped case study tells the story of Joyce, a biology student who notices the development of some unusual symptoms (foot slapping and slurred speech) in her mother. In an effort to understand the cause, Joyce views a documentary-style trigger v...

A Botched Botox Party in the Hamptons

By Adam J. Kleinschmit

This flipped case study explores how the topics of membrane structure, transport, and signaling via membrane-bound receptors are intimately associated with the paralysis of muscle targeted by botulinum neurotoxin. The case scenario revolves around a ...

From Twiggy to Tubby

By Abigail R. Wilson, Ashley E. Rhodes, Timothy G. Rozell

This case study explores the topics of diffusion, osmosis, membrane transport, and the physiological significance of glucose and insulin in the human body. The story begins with a high school athlete, Timmy, who is incredibly efficient at metabolizin...

Antibiotic Resistance in a Russian Prison

By Christian Angeles, Isabella Villano, Andrea C. Nicholas

In this case study, students will have the opportunity to model the spread of tuberculosis and development of antibiotic resistance in a hypothetical prison environment. After reading a brief handout and viewing a short video, students play a simulat...

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