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Favorite Demonstration: Using Calcium and Calcium Binding Proteins To Teach Signal Transduction in Cell Physiology—Demonstrating Conformational Changes of Proteins Using the Simple yet Powerful Technique of PAGE

Journal of College Science Teaching—May 1998

This exercise teaches students science by demonstrating the ability of calmodulin to bind and lose calcium with attendant alterations in protein conformation. To visualize conformation changes using the simple yet powerful technique PAGE provides students with a hands-on method of studying and remembering the concept of molecular movement and ligand binding.
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