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  • Designer DNA

    Book Chapter | September 2018

    This lesson asks students to develop a synthetic genetic code to minimize the change in amino acid sequence in a protein due to mutations, within given criteria and constraints. Students compile and analyze data for…

  • DNA Structure

    Book Chapter | May 2014

    The purpose of this lab is to introduce the concept of deoxyribonucleic acid (DNA) and to define ”What Is the Structure of DNA?” The lab explains how genetic information is stored, transferred, and conserved and also…

  • DNA Isolation and Analysis

    Book Chapter | March 2009

    In this unit, students will isolate DNA suitable for sequencing and other analyses. Students use bioinformatics software to find differences between normal and mutant DNA sequences, then use DNA restriction mapping to…

  • DNA, Genes, and Chromosomes

    Book Chapter | March 2011

    The purpose of this assessment probe is to elicit students’ ideas about structures they encounter when they learn about heredity. The probe is designed to reveal students’ ideas about the “parts and wholes” relationship…

  • DNA Family Relationship Analysis (Genetics)

    Book Chapter | November 2012

    The purpose of the activity, in this chapter, is to help students understand the molecular basis of heredity and the role that DNA technology can play in solving social problems. This activity also helps students learn…

  • Undergraduate Student Conceptions of DNA and Their Understanding of Basic Science

    Journal Article | April 2021

    An understanding of basic science is central to student success at the university level, even for students who will never work in scientific fields. Our investigation into students’ understanding of DNA is part of a…

  • A New Twist on DNA Extraction

    Journal Article | February 2019

    Argumentation is a key scientific practice and a central social and cultural process contributing to the generation, evaluation, and application of new scientific knowledge. As scientists develop arguments and construct…

  • From DNA to Proteins

    Journal Article | August 2018

    Learning tertiary folding through problem solving

  • Decoding Careers in DNA

    Journal Article | July 2018

    Genetic coding lesson brings computational biology and STEM careers to life

  • Modeling DNA

    Journal Article | July 2016

    Understanding the structure of DNA through models and motion.

  • Pass the DNA, Please

    Journal Article | February 2016

    Play a modified game of “Telephone” to learn about transcription, translation, and gene expression.

  • From DNA to Disorder

    Journal Article | July 2005

    The fact that one little letter out of three billion can really make a difference in the genetic makeup of an individual is often difficult for high school students to grasp. Molecular biology is a challenging topic to…

  • DNA Mapping Made Simple

    Journal Article | February 2004

    The universality of the genetic code has allowed DNA isolated from a specific organism to be transferred and incorporated in another organism, transforming bacterial, yeast, plant, and animal cells. This transformation…

  • Idea Bank: Pipe Cleaner DNA

    Journal Article | May 2004

    The pipe cleaner DNA model uses simple materials, but offers limitless opportunities for realistic manipulation, including DNA replication, mutation, and protein synthesis. The activity is also appropriate for students…

  • Extracting the Max From a DNA Extraction

    Journal Article | January 2009

    Students of all ages get a thrill out of actually seeing clumps or strands of DNA. The Biotechnology/Bioinformatics Discovery! Project, a professional development workshop offered to science teachers, has always…

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