In this problem, a group of students tries to explain the genetic cause of calico and tortoiseshell coat color in cats. The challenge to students is to describe the genetics of calico cats by explaining the inheritance of three genes—spotting, black, and orange—and explain why male cats are rarely calico. These coat colors are examples of common patterns of inheritance, so cats make a good model for learning how to predict the appearance of offspring and explain observed results. Another advantage in using cats is that there is much research published explaining the genes. A materials list, teacher background information, safety practices, references, assessment, and outcomes are provided. This book selection includes the Table of Contents, Preface, Catalog of Problems, Acknowledgments, About the Authors, References, and Index.