In this chapter, doctors are unsuccessful in reviving a patient who is an organ donor. The students are called upon to perform the donation surgery, with the job of identifying and removing various organs from the patient’s body. In the United States, a person needs to “opt-in” to be considered an organ donor. In some countries, a person is an organ donor until they “opt out.” Students are asked if they would vote for or against an “opt out” if offered in the United States, and to justify their position. This Teacher Guide chapter highlights the Before the Lesson, During the Lesson, and After the Lesson instructions and recommends that the teacher read prior to starting the lesson. To learn more about the Student Edition chapter referenced here, check out “Emergency! Lab 7: Performing Surgery.”