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Breathing Easy About New Air Pollution Standards

By Kathryn L. Rowberg

A town meeting is the backdrop for a role-playing case about ground-level ozone air pollution. The case consists of a flier and scripts drawn from public comment records on the government mandate to reduce ground-level ozone by limiting nitrogen oxid...

Is Iron Fertilization Good for the Sea?

By LeLeng To Issacs (rr)

This case study describes experiments to seed the ocean with iron to encourage algae growth. It explores how human activities contribute to greenhouse effects and global warming, proposals to potentially counteract these effects and make the ocean mo...

Sickle Cell Anemia

By Debra L. Stamper

In this case study on sickle cell anemia, students are introduced to some of the key researchers responsible for determining the molecular basis of the disease and learn about the functioning of erythrocytes as well as the notion that changes in the ...

The Missing Link

By M. Elizabeth Strasser

The setting for this case study is a paleontological dig in East Africa, where “Sam,” an American undergraduate student, has unearthed part of what appears to be an ancestral human skull. Students read the case story and then, in the lab, they ex...

Can a Genetic Disease Be Cured?

By Michael S. Hudecki (rr)

In this discussion case, parents must decide whether or not to enroll their sons in an experimental treatment program designed to alleviate the symptoms of muscular dystrophy. The case explores the genetics and physiology of the disease as well as th...

Microbial Pie, or What Did You Feed the Neighbors?

By Theresa Hornstein

The Emergency Room seems busier than usual, and the cases coming in are all too similar.  Everyone seems to be suffering from the same symptoms - abdominal pain, vomiting, and bloody diarrhea.  Once the hospital staff identify the bacteria ...

Of Mammoths and Men

By Nancy A. Schiller, Clyde Freeman Herreid

The discovery of a mammoth frozen in the Siberian tundra is the backdrop for this case study, which explores theories for the extinction of the great Ice Age mammals and Homo neanderthalensis....

Should Dinosaurs Be Cloned from Ancient DNA?

By Constance M. Soja, Deborah Huerta

Michael Crichton's Jurassic Park, as a novel and then a blockbuster movie, reawakened the public's fascination with dinosaurs. Although dinosaurs have always been popular, Spielberg's sophisticated cinema computer graphics thrilled human imagination ...

Endangered? The Scenic St. Croix River

By Pamela Davis (rr)

Managing the St. Croix River has sparked tremendous controversy due to conflicting uses of the river. At risk is the water quality and aesthetic value of this National Scenic Riverway. The drama unfolding around the St....

Torn at the Genes

By Jennifer Nelson, Clyde Freeman Herreid

The setting for this case is the family dinner table, where a heated discussion about genetically altered foods is taking place. Marsha Cumberland’s brother-in-law has joined the family for dinner. Ed is an industry official whose job it is to deci...

A Right to Her Genes

By Susannah Gal, Jessie W. Klein

In this true story, students examine the case of a woman with a family predisposition to cancer who is considering genetic testing. Students learn about various aspects of DNA testing and determine how to counsel the woman. The case was designed for ...

A Fridge in Space

By Lok C. Lew Yan Voon

This case analyzes the principles of thermodynamics and the operating cycle of an adiabatic demagnetizing refrigerator (ADR), a piece of equipment NASA uses to keep x-ray detectors cold enough to work.  A synthesis of all the basic principles of...

Is That Pill You're Taking Safe?

By Janis Hammer

This dilemma cased is based on the actual development, FDA approval, and market withdrawal of dexfenfluramine, a drug used in the late 1990s in combination with phentermine for weight loss....

Bad Blood

By Ann W. Fourtner, Charles R. Fourtner, Clyde Freeman Herreid

The ethics of human experimentation are explored in this case about the infamous syphilis studies performed at the Tuskegee Institute from the 1930s to the 1960s. Sponsored by the U.S. Public Health Service, 399 African American men with syphilis wer...

Filthy Lucre

By Ed Acheson

"Tom Brown" is arrested at the airport on his way home for winter break and charged with possession of cocaine when a drug sniffing dog detects traces of the narcotic in his carry-on bag. Some of the money he is carrying has apparently been contamina...

Studying Racial Bias

By Jane Marantz Connor

Students evaluate a research proposal to determine if it is consistent with ethical principles and federal guidelines for conducting research with human subjects. The case can be taught either as a discussion case or using role-playing.  This ca...

The Deforestation of the Amazon

By Philip Camill

In this case study, students examine tropical deforestation in the Amazon from the perspective of three dominant stakeholders in the region: a peasant farmer, logger, and environmentalist. As part of the exercise, students perform a cost-benefit anal...

Should Bill Buy Sammy?

By Jessie W. Klein

In this case, students are shown the relevance of chemistry in daily decision-making by taking a look at the popular dietary supplement, s-adenosylmethionine (SAMe), widely used in Europe for depression, arthritis, and liver disease and now available...

Childbed Fever

By Christa Colyer

This case describes the pioneering work of Ignaz Semmelweis and his efforts to remedy the problem of childbed fever in mid-19th century Europe.  Its purpose is to teach students about the scientific method by "dissecting" the various steps invol...

The Galapagos

By Nancy A. Schiller, Clyde Freeman Herreid

Using problem-based learning and role-playing, students analyze the geological origins of the Galapagos Islands, their colonization, species formation, and threats to their biodiversity in this story of a graduate student caught between local fisherm...

A Search for the Right Answer

By Ann W. Fourtner, Charles R. Fourtner, Clyde Freeman Herreid

In this role-playing case study on Parkinson’s disease, students learn about brain injury and brain repair mechanisms, the physical and psychological effects of a degenerative disease on a patient and her family, the ethics of fetal tissue research...

The Slippery Slope of Litigating Geologic Hazards

By David L. Ozsvath

This case, based on a lawsuit brought against the County of Los Angeles by homeowners suing over damage to their homes in the wake of the Portuguese Bend Landslide, teaches students principles of landslide movement while illustrating the difficulties...

The Dating Game

By Shoshana Tobias, Clyde Freeman Herreid

In this role-playing case study, students attempt to determine the identity of a variety of human fossils based on characteristics described during a “quiz show.”  The case was designed to be used in a general biology class for freshman stud...

AIDS and the Duesberg Phenomenon

By Clyde Freeman Herreid

Renowned virologist and member of the prestigious National Academy of Science, Peter Duesberg has argued that AIDS is not caused by HIV, but is the result of recreational and anti-HIV drugs.  In this PBL case, students read Duesberg’s 1999 art...

The Wolf, the Moose, and the Fir Tree

By Gary M. Fortier

In this analysis case, students study predator-prey dynamics in the Isle Royale National Park ecosystem drawing on data and findings from the article “Wolves, Moose, and Tree Rings on Isle Royale” by B.E. McLaren and R.O. Peterson published in 19...

Needles and Pins

By Lynn Austin

This case, designed for medical students, dental students, and dental hygiene students, covers the steps involved in preventing and responding to accidental needle sticks in the clinical setting.  The case is particularly helpful for use with st...

Seven Skeletons and a Mystery

By Clyde Freeman Herreid

This problem-based learning case uses Archaeopteryx, the most famous fossil in the world, to show the vital role that fossils play in understanding evolutionary history and to explore the different theories for the origin of flight and the debate ove...

Baffled by the Baby Bottle

By Michael A. Jeannot

This case is based on an actual article entitled "Baby Alert" that appeared in Consumer Reports (May 1999). The article raises some concerns about the safety of polycarbonate baby bottles, and recommends that parents dispose of them as a precaution. ...

Avogadro Goes to Court

By Joseph Bieron, Frank J. Dinan

This case study was inspired by a successful lawsuit brought by students against a professor at Pace University who had assigned them the task of calculating the cost of a single aluminum atom in a roll of aluminum foil. The case deals with the conce...

Salton, A Sea of Controversy

By Kristin B. Vessey

The Salton Sea is an “accidental” lake that receives used irrigation water from the Colorado River. Humans have profoundly altered the area’s ecosystems. The Salton Sea is important for wildlife and recreation, but is now saltier than the ocean...

A Case in Point

By Mary Walczak, Juliette Lantz

This case was developed for use in the first weeks of a course in order to show students how participating in active learning exercises in their classes can benefit them. It uses the fictionalized story of a manager of a scientific consulting firm wh...

The Benign Hamburger

By Graham F. Peaslee, Juliette Lantz, Mary Walczak

In this dilemma case study, the executives of a popular restaurant chain must decide whether to use irradiated meat, in this case, beef, to protect its customers from the bacteria, E. coli. Students learn about food irradiation and discuss issues rel...

A Light on Physics

By Richard T. Brundage

This case study presents students with the challenge of working together in teams to win a photography contest. Some team members believe in aperture priority: pictures should be taken with as large an f-number as possible. The other members advocate...

The Bear Facts

By Grace A. Wang

In this decision case, students consider the pros and cons of reintroducing grizzly bears into the northwestern United States as they learn about natural resource policy and the wildlife management decision-making process. Students consider four diff...

Hemophilia

By Yelena Aronova-Tiuntseva, Clyde Freeman Herreid

This case deals with the genetics of the hemophilic condition that afflicted the royal families of Europe.  Students trace the pedigrees of the descendants of Queen Victoria and the passage of the recessive X-linked trait from ancestor to ancest...

The Death of Baby Pierre

By Clyde Freeman Herreid

This directed case study on a genetic disorder was developed for an exam on genetics for a general biology course.  The case is based on an article by scientist and author Jared Diamond titled “Founding Fathers and Mothers” that appeared in ...

So, What is it that Engineers Do, Anyway?

By Ann Bisantz, Amjad Aref, Alexander Cartwright

In this case study, new engineering students are introduced to the discipline of engineering by illustrating the roles of various types of engineers in a large engineering project, the intelligent transportation system, that has the potential to impa...

Life on Mars

By Bruce C. Allen, Clyde Freeman Herreid

This case explores the question of whether there was ever life on Mars and in doing so explores how we define life. The backdrop for the case is the 1996 revelation by NASA of evidence of life on Mars. Through a fictionalized account of the events, t...

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